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马宁

发布日期:2024-03-19    作者:     来源:    点击:


个人概况

马宁  

回  导师层次博导

技术职称研究员  导师类型学术型

最后学历博士研究生  最后学位理学博士

工作单位广州国家实验室  邮箱:ma_ning@gzlab.ac.cn

个人简介(300字以内

马宁,广州实验室研究员,本科毕业于中国海洋大学,博士毕业中国科学院广州生物医药与健康研究院,之后赴斯坦福大学医学院进行博士后、讲师等工作。马宁研究员于20209月回国加入生物岛实验室,20221月加入广州实验室,课题组聚焦于心肺发育及慢性心肺疾病的发病机制研究。以第一作者发表论文于CirculationNature Biomedical EngineeringJBC等期刊,他引1300多次。曾获得广东省自然科学一等奖,广东省重大人才项目青年拔尖人才,黄埔区精英人才美国AHA Postdoc FellowshipAHA Career Development Award

研究方向

1、心肺发育

2、慢性心肺疾病的发病机制

代表性第一和通讯作者论文

(1)Belbachir N, Wu Y, Shen M, Zhang SL, Zhang JZ, Liu C, Knollmann BC, Lyon GJ#, Ma N#, Wu JC#. Studying Long QT Syndrome Caused by NAA10 Genetic Variants Using Patient-Derived Induced Pluripotent Stem Cells. Circulation. 2023; 148:1598-1601.

(2)Barndt RJ*, Ma N*, Tang Y, Haugh MP, Alamri LS, Chan SY, Wu H. Modeling of dilated cardiomyopathy by establishment of isogenic human iPSC lines carrying phospholamban C25T (R9C) mutation (UPITTi002-A-1) using CRISPR/Cas9 editing. Stem Cell Research. 2021. doi:10.1016/j.scr.2021.102544.

(3)Ma N, Zhang S, Wu J. Complex heritability in cardiomyopathy. Nature Biomedical Engineering. 2019; 3:87-89.

(4)Ma N*, Zhang J*, Itzhaki I*, Zhang S, Chen H, Haddad S, Kitani T, Wilson K, Tian L, Shrestha S, Wu H, Lam C, Sayed N, Wu J. Determining the Pathogenicity of a Genomic Variant of Uncertain Significance Using CRISPR/Cas9 and Human Induced Pluripotent Stem Cells. Circulation. 2018; 138:2666–2681.

(5)Ma N*, Shan Y*, Liao B*, Kong G*, Wang C, Huang K, Zhang H., Cai X, Chen S, Pei D, Chen N, and Pan G. Factor-induced Reprogramming and Zinc Finger Nuclease-aided Gene Targeting Cause Different Genome Instability in beta-Thalassemia Induced Pluripotent Stem Cells (iPSCs). The Journal of Biological Chemistry. 2015; 290:12079-12089.

(6)Ma N*, Liao B*, Zhang H, Wang L, Shan Y, Xue Y, Huang K, Chen S, Zhou X, Chen Y, Pei D, Pan G. Transcription activator-like effector nuclease (TALEN)-mediated gene correction in integration-free beta-thalassemia induced pluripotent stem cells. The Journal of Biological Chemistry. 2013; 288: 34671-34679.