![](/__local/2/18/F2/A508C9547E1BE4C2E7458F1C4FB_FF29EAD0_9BF2.jpg)
个人概况
姓名:冯国帅 性别:男
职称:教授 导师资格:研究生导师,博士后合作导师
单位:广州医科大学基础医学院
学历:博士研究生 毕业院校:中山大学
招生专业: 病理学与病理生理学,免疫学
电子邮件: gfeng@gzhmu.edu.cn
通信地址:广州市番禺区广州医科大学
研究方向
致力于探索心脏疾病的免疫学机理及治疗策略,主要研究心梗损伤及病毒性心肌炎中的骨髓系免疫细胞(单核/巨噬细胞和中性粒细胞等)对心脏功能的影响,并通过二代测序来探索损伤的炎性心脏中的基因变化,发现并开发心梗及病毒性心肌炎的免疫治疗靶点。
所获荣誉
2023年3月,入选广州医科大学“南山学者(骨干人才)”人才计划。
工作经历
2017年-2022年,于美国圣路易斯华盛顿大学医学院心血管中心从事博士后研究工作,合作导师为Kory Lavine。
部分代表性论文:
1) Guoshuai Feng, et.al and Kory Lavine*. CCL17 aggravates myocardial injury by suppressing recruitment of regulatory T cells. Circulation, 2022;145:765–782. 第一作者,心血管顶刊,影响因子:39.922。
2) Guoshuai Feng, et.al and Kory Lavine*. CCL17 protects against EMCV induced myocarditis by suppressing recruitment of regulatory T cells. Journal of the American Heart Association, 2023, 12(4):e028442. 第一作者,美国心脏协会会刊,影响因子:6.106。
3) Feng, Guo-shuai, et.al and Liu, Pei-qing*. Synthesis of the novel PARP-1 inhibitor AG-690/11026014 and its protective effects on angiotensin II-induced mouse cardiac remodeling, Acta Pharmacologica Sinca, 2017, 5(38): 638-650. 第一作者,影响因子:7.169。
4) Wenjun Li, Guoshuai Feng, et.al, Kory J. Lavine* and Daniel Kreisel*. Ferroptotic cell death and TLR4/Trif signaling initiate neutrophil recruitment after heart transplantation, Journal of Clinical Investigation, 2019, 129(6): 2293-2304. 第二作者,影响因子:19.456。
5) Gyu Seong Heo, Benjamin Kopecky, Deborah Sultan, Guoshuai Feng, et.al, Yongjian Liu*. CCR2-targeted PET imaging of injured heart. Journal of nuclear medicine. 2019;98. 第四作者,影响因子:11.082。
6) Gyu Seong Heo, Benjamin Kopecky, Deborah Sultan, Monica Ou, Guoshuai Feng, et.al, Yongjian Liu* and Kory Lavine*. Molecular Imaging Visualizes Recruitment of Inflammatory Monocytes and Macrophages to the Injured Heart. Circulation Research, 2019;124:881–890. 第五作者,影响因子:23.213。
7) Nicole R. Wong, Jay Mohan, Benjamin J. Kopecky, Shuchi Guo, Lixia Du, Jamison Leid, Guoshuai Feng, et.al, and Kory Lavine*. Resident cardiac macrophages mediate adaptive myocardial remodeling. Immunity. 2021;54(9):2072-2088. 第七作者,影响因子:43.474。
8) Ping He, Zhuoming Li, Zhongbao Yue, Hui Gao, Guoshuai Feng, et.al, and Peiqing Liu*. SIRT3 prevents angiotensin II-induced renal tubular epithelial-mesenchymal transition by ameliorating oxidative stress and mitochondrial dysfunction. Molecular and Cellular Endocrinology, 2018;460:1-13. 第五作者,影响因子:4.368。
9) Guoshuai Feng, et al. and Jie Jiang*. Protective effect of chinonin in MPTP-induced C57BL/6 mouse model of Parkinson's disease. Biological and Pharmaceutical Bulletin. 2014, May. DOI: 10.1248/bpb.b14-00128. 第一作者,影响因子:2.264。
10) Pan-xia Wang, Zhuo-ming Li, Si-dong Cai, Jing-yan Li, Ping He, Yi Huang, Guo-shuai Feng, et.al, and PeiqingLiu. C33(S), a novel PDE9A inhibitor, protects against rat cardiac hypertrophy through upregulating cGMP signaling. Acta Pharmacologica Sinica, 2017;38:1257–1268. 第七作者,影响因子:7.169。