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个人概况
姓名: 牛学锋 性别:男
职称:副研究员 导师资格:硕士研究生导师
单位:广州医科大学附属第一医院
学历: 博士研究生 毕业院校:华南农业大学
招生专业: 免疫学
电子邮件: niuxuefeng@gird.cn
通信地址: 广州市越秀区东风西路195号
研究方向
新发突变传染病抗体研究,免疫组学研究,
所获荣誉
1. 广州市高层次人才后备人才
科研项目
1、SARS-CoV康复者接种新型冠状病毒疫苗后抗体组库分析及抗体应答机制研究,国自然面上项目,58万元,主持,在研
2、运用高通量测序抗体组库、单细胞克隆及生物信息学研究流感疫苗免疫后 的抗体反应及机制,广州市科技计划重点项目 200万元,参与,结题
部分代表性第一和通讯作者论文:
1. Liang, H., Zheng, P., Wang, Q., Deng, Y., Liang, D., Yi, H., Cheng, Y., Zhao, X., Ma, J., Yang, Y., Hu, P., Zheng, P., Zhang, Y., Huang, S., Lin, X., Ke, C., Niu, X.#, Sun, B.#, Chen, L.#, 2022. Broad and durable antibody response after vaccination with inactivated SARS-CoV-2 in individuals with a history of 2003 SARS-CoV infection. Emerg Microbes Infect, 1-20.
2. Zhang, Y., Yan, Q., Luo, K., He, P., Hou, R., Zhao, X., Wang, Q., Yi, H., Liang, H., Deng, Y., Hu, F., Li, F., Liu, X., Feng, Y., Li, P., Qu, L., Chen, Z., Pan-Hammarstrom, Q., Feng, L., Niu, X.#, Chen, L.#, 2022. Analysis of B Cell Receptor Repertoires Reveals Key Signatures of the Systemic B Cell Response after SARS-CoV-2 Infection. J Virol 96, e0160021.
3. Yan, Q., He, P., Huang, X., Luo, K., Zhang, Y., Yi, H., Wang, Q., Li, F., Hou, R., Fan, X., Li, P., Liu, X., Liang, H., Deng, Y., Chen, Z., Chen, Y., Mo, X., Feng, L., Xiong, X., Li, S., Han, J., Qu, L., Niu, X.#, Chen, L.#, 2021. Germline IGHV3-53-encoded RBD-targeting neutralizing antibodies are commonly present in the antibody repertoires of COVID-19 patients. Emerg Microbes Infect 10, 1097-1111.
4. Niu, X., Li, S., Li, P., Pan, W., Wang, Q., Feng, Y., Mo, X., Yan, Q., Ye, X., Luo, J., Qu, L., Weber, D., Byrne-Steele, M.L., Wang, Z., Yu, F., Li, F., Myers, R.M., Lotze, M.T., Zhong, N., Han, J., Chen, L., 2020. Longitudinal Analysis of T and B Cell Receptor Repertoire Transcripts Reveal Dynamic Immune Response in COVID-19 Patients. Front Immunol 11, 582010.
5. Niu, X., Yan, Q., Yao, Z., Zhang, F., Qu, L., Wang, C., Wang, C., Lei, H., Chen, C., Liang, R., Luo, J., Wang, Q., Zhao, L., Zhang, Y., Luo, K., Wang, L., Wu, H., Liu, T., Li, P., Zheng, Z., Tan, Y.J., Feng, L., Zhang, Z., Han, J., Zhang, F., Chen, L., 2020. Longitudinal analysis of the antibody repertoire of a Zika virus-infected patient revealed dynamic changes in antibody response. Emerg Microbes Infect 9, 111-123.
6. Niu, X., Zhao, L., Qu, L., Yao, Z., Zhang, F., Yan, Q., Zhang, S., Liang, R., Chen, P., Luo, J., Xu, W., Lv, H., Liu, X., Lei, H., Yi, C., Li, P., Wang, Q., Wang, Y., Yu, L., Zhang, X., Bryan, L.A., Davidson, E., Doranz, J.B., Feng, L., Pan, W., Zhang, F., Chen, L., 2019. Convalescent patient-derived monoclonal antibodies targeting different epitopes of E protein confer protection against Zika virus in a neonatal mouse model. Emerg Microbes Infect 8, 749-759.
7. Ma, J., Cheng, Z., Xue, M., Huang, H., Li, S., Fang, Y., Zeng, Y., Lin, R., Liang, Z., Liang, H., Deng, Y., Cheng, Y., Huang, S., Wang, Q., Niu, X.#, Li, S.#, Zheng, P.#, Sun, B.#, 2022. Investigation of antibody levels during three doses of Sinopharm/BBIBP vaccine inoculation. Front Immunol.
8. Zhang, Q., Gui, M., Niu, X., He, S., Wang, R., Feng, Y., Kroeker, A., Zuo, Y., Wang, H., Wang, Y., Li, J., Li, C., Shi, Y., Shi, X., Gao, G.F., Xiang, Y., Qiu, X., Chen, L., Zhang, L., 2016. Potent neutralizing monoclonal antibodies against Ebola virus infection. Sci Rep 6, 25856.